12 Best Museums In South Carolina

South Carolina is a state known for its pristine beaches, rolling state parks, and a treasury of Civil War-era historical artifacts. The history of the state dates back to the 16th century, when early French and Spanish settlers arrived. The first European permanent settlement was established in 1670 near present day Charleston. Settlers named the colony "Carolina" after King Charles I, and it was later divided in 1710 into South Carolina and North Carolina.With such a longstanding history, South Carolina has many stories to tell from people of a variety of backgrounds. You can uncover these stories and much more in the treasury of museums in the state. Here are 12 of the best museums in South Carolina you need to visit.

South Carolina State Museum: Columbia

The South Carolina State Museum in downtown Columbia is the state’s largest and most comprehensive. Spanning four floors, it features exhibits on natural history, art, science, and technology, including a 4D theater, planetarium, and observatory. Visitors can marvel at a life-sized megalodon model or learn about South Carolina’s industrial past. The museum is housed in a beautifully restored 1894 textile mill, adding to its charm. Be sure to walk the scenic Columbia Riverwalk that stretches along the Congaree River or stop at Motor Supply Co. Bistro in the Vista for a locally inspired lunch.

Columbia Museum of Art: Columbia

The Columbia Museum of Art is a cultural landmark that brings global creativity to South Carolina’s capital. Its galleries feature everything from Renaissance paintings and Baroque sculptures to bold contemporary works and photography. The museum regularly hosts rotating exhibitions and art workshops, making it a lively hub for creativity and community engagement. Its modern layout and central location make it easy to explore before heading out for a stroll. Visit Soda City Market on Main Street for local crafts and street food, or check out a concert or sports event at Colonial Life Arena after your artistic endeavor.

The Children’s Museum of the Upstate: Greenville

The Children’s Museum of the Upstate is one of the largest children’s museums in the Southeast and a paradise for young learners. With dozens of interactive exhibits, it encourages kids to explore science, engineering, and creativity through play. Highlights include a kid-sized grocery store, a hands-on water exhibit, and an art studio. The museum’s cheerful, modern design reflects Greenville’s vibrant downtown energy. Visiting families can take a short walk to Falls Park on the Reedy to see waterfalls and gardens, or visit the Greenville Zoo for an afternoon surrounded by wildlife.

Upcountry History Museum: Greenville

For those curious about the Palmetto's role in American history, the Upcountry History Museum offers a Smithsonian-affiliated experience that’s both educational and engaging. Exhibits chronicle the region’s story from Native American settlements to industrial development, featuring artifacts, photographs, and immersive media. Rotating exhibits highlight themes like World War II, civil rights, and the textile boom that shaped modern Greenville. Relax and get a little caffeinated refreshment at Methodical Coffee, a local favorite, or take in a show at The Peace Center, Greenville’s premier performing arts venue, located just a few blocks away from the museum.

Franklin G. Burroughs-Simeon B. Chapin Art Museum: Myrtle Beach

Overlooking the ocean, the Chapin Art Museum brings a breath of creativity to Myrtle Beach. The museum showcases regional and national artists through frequently changing exhibits that emphasize coastal culture, fine art, and photography. Visitors can also take art classes or explore the sculpture garden that frames the building’s classic Southern architecture. Its serene location makes it a quiet retreat from the beach crowds. If you want more beachside time, walk across to Myrtle Beach State Park for ocean views and trails, or enjoy shopping and dining at The Market Common, just a few minutes away.

The Charleston Museum: Charleston

Founded in 1773, The Charleston Museum holds the title of America’s first museum and remains one of its finest. Exhibits tell the story of Charleston’s past — from prehistoric fossils to colonial artifacts and Civil War relics. The museum also operates two nearby historic homes that showcase period furnishings and architecture. Visitors can easily spend hours exploring the Lowcountry’s layered history. Take in more historical wonder by touring the elegant Joseph Manigault House, which is managed by the museum. End the day walking through the Charleston City Market, one of the nation’s oldest public markets, to see a selection of handmade goods and try some local food.

International African American Museum: Charleston

Perched on the historic Gadsden’s Wharf, where many enslaved Africans first arrived in the United States, the International African American Museum offers one of the most profound cultural experiences in the South. Opened in 2023, it tells a global story of resilience and legacy through immersive exhibits, interactive maps, and personal narratives. The building itself overlooks the harbor in silent tribute. Visitors can also relax at Waterfront Park, famous for its Pineapple Fountain and coastal breezes, or enjoy dinner at Fleet Landing, a waterfront restaurant known for fresh seafood and harbor views.

Coastal Discovery Museum: Hilton Head Island

The Coastal Discovery Museum, set on 68 acres of lush coastal land, celebrates the natural beauty of Hilton Head Island and the Gullah Geechee culture of the Lowcountry. Visitors can explore walking trails shaded by centuries-old oaks, visit butterfly gardens, and learn about the area’s delicate ecosystems. The museum is also part of the Gullah Heritage Corridor, preserving one of the nation’s most unique cultural identities. Don’t forget to take a guided tour at the Hilton Head Distillery to learn how local spirits are made, or spend the afternoon sunbathing and swimming at Coligny Beach Park.

Patriots Point Naval & Maritime Museum: Mount Pleasant

At Patriots Point in Mount Pleasant, naval history comes alive aboard the mighty USS Yorktown, a World War II aircraft carrier turned floating museum. Visitors can explore flight decks, submarine interiors, and exhibits dedicated to the Vietnam War and the Medal of Honor. The site also honors generations of American servicemembers. Its location on Charleston Harbor provides breathtaking water views. Continue your adventure walking or biking the Arthur Ravenel Jr. Bridge for panoramic scenery, or grab a bite at The Wreck of the Richard & Charlene, a local favorite serving fresh seafood right on the water.

South Carolina Railroad Museum: Winnsboro

The South Carolina Railroad Museum in Winnsboro offers an expansive journey into the state’s railroading past. It showcases a variety of historic locomotives, cabooses, and rail cars, along with a museum full of rail artifacts. Guests can even hop aboard for a train ride through the countryside, a highlight for families and history buffs alike. Continue to appreciate the sights of Winnsboro by touring the Downtown Winnsboro area to see the 19th-century Town Clock, or head to Lake Wateree State Park for boating, fishing, and relaxing along the coastal shore.

The Rice Museum: Georgetown

In the waterfront town of Georgetown, the Rice Museum tells the story of South Carolina’s once-booming rice industry that helped shape the state’s early economy. Housed in two historic buildings, the museum features exhibits on maritime history, plantation life, and local artisanship. It’s an intimate and educational stop in one of South Carolina’s most endearing small towns. Take in more of the local scene and stroll along Georgetown’s Harborwalk, lined with restaurants and boutiques, or take some time to tour the Kaminski House Museum, a sophisticated 18th-century home overlooking the Sampit River.

World of Energy: Seneca

The World of Energy museum in Seneca is operated by Duke Energy and offers a fascinating look at how electricity powers modern life. Visitors can explore interactive exhibits on hydroelectric and nuclear energy, as well as scenic trails overlooking Lake Keowee, a human-made reservoir initially made to serve the needs of Duke Energy, but also functions as a popular spot for public recreation. The museum emphasizes sustainability and South Carolina’s role in energy innovation. You can refresh your mind after the day’s learning with a peaceful picnic beside the lake or visit South Cove County Park for kayaking, swimming, and some of the Upstate’s best sunset views.

Discover the Story of the Seaboard State

South Carolina is more than a stop for sunsets and shopping. It has a centuries-long history that tells the story of how everyone from Indigenous people, enslaved peoples, and settlers built an agricultural and industrial powerhouse. The state stands as a living museum of America’s tradition of innovation and invention amidst civil struggles for progress. From rice to Renaissance art, you can find it within South Carolina’s borders. And there is no better way to discover the continuing history of the state than with a tour through its numerous museums and attractions. Which one are you going to first?