11 Best Places To Live In The Southern United States In 2025
Maybe it's the scrumptious food, the four-season charm, or the endless greenery that pulls you in; whatever the reason, the American South is easily one of the most dynamic and inviting regions in the United States. Spanning over a dozen states, it is home to a rich mix of lively cities and small towns, a significant stretch of the Appalachian Mountains, scenic coastlines, and miles of rolling farmland. Summers bring beach days, while fall turns the mountains into a canvas of fiery colors. And when winter hits, the slopes welcome skiers from all around.
Whether you're eyeing the vibrant culture of Charleston or the peaceful Ozark views in Fayetteville, this region is full of surprises. Here is the list of the 11 best places to live in the South based on affordability, job opportunities, quality of education, and overall well-being, among other details.
Charleston, South Carolina
Ranked as the best place to live in the United States by U.S. News & World Report, Charleston is suitable for young professionals and families looking to plant their roots. It attracts families and retirees looking for a balanced and enriching lifestyle, thanks to its walkable historic districts, excellent healthcare, and top-rated educational facilities. For example, the College of Charleston is one of the oldest institutions of its kind in the state, with over 150 buildings. At the same time, the Medical University of South Carolina provides healthcare education. Ode to the medical university, the city is also home to renowned healthcare facilities such as MUSC Health University Medical Center and Roper Hospital, providing top-tier medical services.
Residents can easily access nearby beaches like Folly Beach and Sullivan’s Island, offering weekend escapes just minutes from downtown. The city’s vibrant cultural calendar includes events like the Spoleto Festival USA, a 17-day celebration of performing arts, and history lovers can explore iconic attractions like Fort Sumter National Monument, where the first shots of the Civil War were fired.
Columbia, South Carolina
Columbia, the capital of South Carolina, is filled with history, culture, and outdoor adventure. Affordability is what makes it stand out. With a median house price of around $230,000, as compared to the state average of $300,000, it offers the perks of a reasonably big city without the big city cost. Columbia’s large student population, anchored by the University of South Carolina, brings energy, diversity, and amenities like cafés, art galleries, and spirited sports events at Williams-Brice Stadium.
It also has a growing job market and a welcoming feel that makes it easy to settle in. Top employers in the city include the Prisma Health hospital system, which provides state-of-the-art medical care for locals. Nature lovers will appreciate Congaree National Park, home to some of the tallest trees in the U.S., and the nearby Riverbanks Zoo & Garden, one of the top-rated zoos in the Southeast. Popular dining spots like Mr. Friendly’s and The Devine Cinnamon Roll Deli round out the local charm.
Richmond, Virginia
Whether you're a young professional, growing a family, or looking for a place to settle down, Richmond offers a bit of everything for everyone. The cost of living is relatively affordable compared to bigger East Coast cities, and the housing market includes historic homes, sleek apartments, and charming bungalows with a median home price of around $360,000 as of May 2025, below Virginia’s average of $400,000. The city balances its deep historical roots with modern energy, making it attractive for creatives and entrepreneurs.
Richmond’s thriving arts and food scene includes gems like Lillie Pearl and Perly’s, while its role as Virginia’s capital offers steady government and education jobs. Virginia Commonwealth University, one of the state's largest and most diverse institutions, adds a youthful buzz and supports health and the arts innovation. The James River Park System offers whitewater rafting, scenic trails, riverfront views, and cultural attractions like the Virginia Museum of Fine Arts and the Science Museum of Virginia, which add plenty to explore year-round.
Charlotte, North Carolina
People looking for career growth, a family-friendly community, or a balanced lifestyle choose Charlotte. It is thriving, desirable, and relatively inexpensive. With a booming economy, especially in finance and tech, it offers job opportunities, and a relatively low cost of living compared to other major U.S. cities. Families are mostly drawn to the suburbs, offering top-rated schools such as Charlotte Country Day School and Providence Day School, as well as green spaces like Freedom Park. Meanwhile, sports fans can catch a Panthers or Hornets game right in the heart of the city. For any medical concerns, the Carolinas Medical Center is one of the best in the region, featuring a Level I Trauma Center and a 24-hour emergency department.
Charlotte fits a wide range of lifestyles. The bustling Uptown district is filled with top-rated restaurants, museums like the Mint Museum and Discovery Place, and a lively nightlife scene. Those looking for a more relaxing environment will adore quaint neighborhoods like Dilworth and NoDa, where there is a sense of community throughout. Even with so much to see and do, and as the most populous city in the state, Charlotte remains affordable, with a median home value of around $400,000 as of May 2025.
Myrtle Beach, South Carolina
With affordable housing, a warm climate, and a powerful sense of community, Myrtle Beach is more than just a getaway; it’s where people build a simple, sun-soaked lifestyle all year. One of the biggest draws is the cost of living, especially regarding housing, with a median home price of approximately $320,000. For seniors who don’t want to live alone, Myrtle Beach features retirement communities like Watercrest. Here, one can avail assisted living or memory care with amenities like a fitness center, a music room, a spa, and dining areas.
There’s always something to do in Myrtle Beach. The Myrtle Beach Boardwalk is a place to watch live music, engage in waterfront dining, and enjoy family-friendly attractions. Foodies can explore popular waterfront spots like Pier 14 with its seafood, or Drafts Sports Bar & Grill to watch a match with your meal. When it comes to amenities, there is no shortage, from the 369-bed Grand Strand Medical Center to the Myrtle Beach International Airport.
Fayetteville, Arkansas
Fayetteville is one of the South’s best-kept secrets, nestled in the Ozark Mountains. It combines small-town charm with modern amenities, making it an ideal place for students, professionals, and families. Those looking for jobs are in luck thanks to some of the town’s top employers, including Walmart, Tyson Foods, and the University of Arkansas. The economy continues to grow, and the median home price sits around $370,000, similar to the national average.
As the home of the University of Arkansas, Fayetteville buzzes with youthful energy and academic opportunities. Residents enjoy live theater at TheatreSquared and performances at the Walton Arts Center. Outdoor enthusiasts can explore trails at Lake Fayetteville Park or hike through the nearby Ozark National Forest and Devil’s Den State Park. Washington Regional Medical Center, a top-rated hospital, serves the area and supports Fayetteville’s healthcare needs. The city also benefits from Ozark Regional Transit, providing bus services to connect neighborhoods and reduce dependence on cars.
Sarasota, Florida
Set along the Gulf Coast, Sarasota combines coastal beauty, culture, and a relaxed lifestyle that appeals to both families and retirees. With nearly 30% of the population being 65 years and above, it’s clear that many seniors are already calling it home. The cost of living is relatively reasonable compared to larger cities, and there’s no state income tax, which is a bonus for residents. Homes for sale have a median listing price of $430,000, which is reasonable for its coastal location. Moreover, the healthcare system is top-notch, anchored by the Sarasota Memorial Health Care System (SMH), one of the largest public health systems in the state.
Sarasota balances laid-back coastal living with artistic sophistication. From the white sands of Siesta Key Beach to the art galleries and performances at The Ringling and Sarasota Opera, residents find peace with refinement. Downtown buzzes with top-tier dining, boutique shopping, and vibrant nightlife. At the same time, surrounding communities like Lakewood Ranch and Palmer Ranch provide a suburban lifestyle with convenient access to parks and schools.
Mount Pleasant, South Carolina
Mount Pleasant offers a relaxed, upscale lifestyle just across the river from Charleston. Its proximity to downtown Charleston and coastal getaways like Sullivan’s Island makes it one of the most desirable suburbs in the South. The town boasts excellent public schools, including Wando High School and Lucy Beckham High, and abundant waterfront parks and green spaces. It is also one of the safest communities in the region, with only 105 violent crimes in 2019 for its 92,000 residents. Compared to other large cities like Rock Hill, which saw nearly 500 violent incidents, residents can rest assured about their safety.
As for activities, Patriots Point Naval & Maritime Museum draws history buffs, while outdoor lovers frequent Shem Creek for kayaking and fresh seafood dining. Mount Pleasant Towne Centre provides shopping, dining, and entertainment in a single walkable space. East Cooper Medical Center serves healthcare needs, and CARTA (Charleston Area Regional Transportation Authority) offers limited bus service, helping reduce local traffic and improving access to Charleston’s city center.
Jacksonville, Florida
Jacksonville stands out for people looking to live in a city that blends affordability, opportunity, and lifestyle. It offers urban living and natural beauty, with over 20 miles of beaches, the St. Johns River, and dozens of parks and preserves for outdoor lovers. What makes Jacksonville appealing is its cost of living, which is lower than many other major Florida cities, without compromising on comforts. The average home in town costs less than $300,000, which is a steal compared to both national and state medians. Moreover, families appreciate the public and private school options, such as The Bolles School, Episcopal School of Jacksonville, and Trinity Christian Academy. At the same time, retirees enjoy the mild winters and access to top-tier medical care at the Mayo Clinic Jacksonville, UF Health Jacksonville, or Baptist Health.
From relaxing on miles of uncrowded beaches to exploring the vibrant arts and food scene in neighborhoods like Riverside and San Marco, Jacksonville offers something for every lifestyle. Outdoor lovers can kayak through the Timucuan Ecological & Historic Preserve or enjoy hiking and wildlife watching at Kathryn Abbey Hanna Park. Families can spend the day at the Jacksonville Zoo and Gardens, while sports fans can catch a Jaguars game or enjoy year-round events at Daily’s Place.
Chattanooga, Tennessee
Chattanooga offers beautiful scenery on the Tennessee River, where people can hike in the morning and enjoy the "Scenic City’s" natural beauty and cultural vibrancy. Chattanooga is an attractive place to live, especially for retirees, with families benefiting from top-rated schools like Chattanooga School for the Arts & Sciences and Baylor School. Erlanger Health System and CHI Memorial Hospital provide excellent healthcare. In addition, the median housing value of $330,000 is just below the state average, providing a comfortable environment for homebuyers.
The city's commitment to green spaces enhances its appeal to nature enthusiasts. The Tennessee River offers opportunities for kayaking, paddleboarding, and scenic riverwalk strolls. Attractions like Lookout Mountain, Ruby Falls, and the Tennessee Aquarium make Chattanooga a favorite for families and weekend explorers alike. The Incline Railway offers stunning views as it climbs the mountain, and nearby Rock City features massive sandstone formations and beautiful gardens, rounding out a full day of adventure.
Tampa, Florida
Located on the Gulf Coast, Tampa is a close-knit town in Florida that boasts warm weather year-round, beautiful beaches, and endless outdoor activities. It offers residents a vibrant lifestyle with a lower cost of living than other major Florida cities. This is evident through the median home price of around $380,000 and the lack of state income tax, making it especially attractive for families and retirees. While being affordable, amenities are plentiful. Top healthcare providers like Tampa General Hospital and AdventHealth Tampa serve the city, ensuring excellent medical care. Families also benefit from strong schools such as Plant High School and Berkeley Preparatory School.
Just a short drive away, beautiful beaches like Clearwater and St. Pete add to Tampa’s appeal, making it a well-rounded destination for both residents and tourists. Residents can also explore historic Ybor City, known for its Cuban heritage, cigar shops, and lively nightlife. For art lovers, the Tampa Museum of Art and the Straz Center for the Performing Arts offer enriching experiences, while sports fans can catch a game with the Tampa Bay Buccaneers or Lightning.
Final Thoughts
Whether you're drawn by the low cost of living, warm climate, job opportunities, or tight-knit communities, the Southern region blends hospitality and lifestyle in a way that few places can. With its mix of culture, nature, and affordability, the Southern United States stands out as a top destination for anyone looking to settle into a place that feels like home. From the scenic mountain towns of Tennessee to the charming coastal cities of Florida and the historic hubs of Virginia and the Carolinas, the South truly offers something for everyone.
