Trastevere had narrow, winding, irregular streets fronted by many original medieval houses. At night the streets are crowded by both Italians and foreigners because of the many pubs and restaurants.
From Via Emanuele, walk south to the Tiber and cross the bridge adjacent to Isola Tiberina. Continue south a very short distance on Viale Trastevere to the Tourist Info Center - marked with a red question mark on the map. Turn right and the church is but a few blocks.
If you cross the Tiber using the Ponte Sisto Bridge - marked #9 on the map - simply walk a few blocks straight into Trastevere and you will run into the church.
If you come by Taxi, tell the driver you want to be dropped off at Piazza Trilussa - marked #7 on the map.
Everyone in Trastevere knows where the church is located, so if you make a wrong turn, just ask for directions. The correct pronunciation is "tras-TEV-va-ray", with the accent on the second syllable.
As a final thought....the Trastevere neighborhood is home to dozens and dozens of great restaurants, and lunch or dinner here along a cobblestone street is a real pleasure, and a real authentic slice of Rome.